Description
PE-22-28 is a synthetic peptide designed to study neuropeptide signaling mechanisms, particularly those associated with neuroprotective and neuroregenerative effects. It is commonly used in in vitro research to evaluate its interaction with specific receptors and to examine its potential role in modulating cellular signaling cascades. The peptide’s precise engineering and stability make it a valuable tool for investigating neural pathways in controlled research settings.
The compound was synthesized through advanced techniques that ensure its high solubility and structural integrity, allowing for consistent results in a variety of laboratory applications. Its ability to engage with neuropeptide receptors and pathways provides significant utility for research into neural communication and potential therapeutic targets for neurodegenerative conditions.
Rigorous development and quality assurance processes ensure that PE-22-28 meets the exacting standards required for cutting-edge in vitro research. Its lyophilized formulation is optimized for long-term storage and ease of reconstitution, making it adaptable to a wide range of experimental conditions.
This product is classified as Research Use Only (RUO) and is not intended for human or veterinary applications. Labs who are ordering reconstitution are advised to consult our terms and conditions for usage guidelines.
| Property | Detail |
| Chemical | PE-22-28 |
| Synonyms | Neuropeptide Analogue PE-22-28 |
| Sequence | Ala-Gly-Lys-His-Pro-Thr-Gly-Asp |
| Molecular Weight | 873.02 g/mol |
| Formula | C40H65N11O12 |
| CAS Number | 123987-16-8 |
| Solid Solubility | Soluble in sterile water |
| Storage | Store at -20°C |
| PubChem CID | 305986521 |


Certificate of Analysis
Lone Star Research ensures the highest quality of PE-22-28 through rigorous analytical testing. The Certificate of Analysis (COA) verifies the compound’s integrity and reliability for research purposes.
| Parameter | Detail | Result |
| Lot number | LSRPE2024-084 | ☑ VALID |
| MFG Date | 11/25/2024 | ☑ VALID |
| Expiration Date | 12/31/2027 | ☑ VALID |
| Appearance | Lyophilized powder | ☑ PASS |
| Solubility | Clear in sterile water | ☑ PASS |
| HPLC | Purity ≥98% | ☑ 99.1% |
| Amino Acid Analysis | Ala, Gly, Lys, His, Pro, Thr, Asp | ☑ PASS |
| Mass Spectrum | 873.02 g/mol | ☑ 873.04 g/mol |
Storage Protocols
Proper storage is critical to maintaining the stability and efficacy of PE-22-28. Exposure to suboptimal conditions can lead to degradation and reduced performance in research applications. Consistent storage conditions are recommended to preserve product integrity.
| Storage Condition | Duration |
| Frozen (-20°C) | Up to 3 years |
| Refrigerated (4°C) | Up to 3 months |
| After Reconstitution | Use within 28 days at 4°C |
- Store in a tightly sealed container to avoid contamination.
- Protect from light to maintain chemical stability.
- Avoid repeated freeze-thaw cycles to prevent degradation.

Lone Star Research Storage Protocols:
Lone Star Research employs advanced storage solutions, including medical-grade freezers and refrigeration systems. Backup generators and continuous temperature monitoring ensure product stability at all times. Temperature logs are recorded to the cloud and audited quarterly to maintain high standards.
Lonestar Reconstitution Protocols:
PE-22-28 is reconstituted under stringent conditions, following sterility guidelines in controlled environments with negative pressure. Reconstituted chemicals are non-returnable due to their sensitive handling requirements.


Lyophilized Powder (Standard)
A freeze-dried, stable form of the chemical, ideal for long-term storage. Typically stable for up to 2 years when stored properly. Keep frozen at -20°C to maintain stability.
Reconstituted (Ready-to-Use) A pre-prepared, liquid form reconstituted with up to 2.5 mL of bacteriostatic water for convenience. Use within 28 days when stored at 4°C after reconstitution.
Signs of Degradation (After Reconstitution):
- Formation of particulates or cloudiness.
- Loss of clarity or discoloration.
- Reduced bioactivity in research applications.
Proper handling and storage are essential to maintain the efficacy of most peptides. Lone Star Research is not responsible for mishandling or temperature fluctuations after the product leaves our facility. Please see our Return policy for more details.

Free FedEx 2 Day Shipping
All research chemicals are shipped free of charge via FedEx 2nd Day Air, using thermally regulated packaging with cold packs to maintain stability during transit. If reconstitution is requested, adherence to temperature requirements is critical to preserve chemical potency. Improper handling may compromise the compound’s efficacy. We only ship Monday – Wednesday to ensure chemicals arrive to your lab in good condition.
| Order by 11pm Monday | Ships Tuesday |
| Order by 11pm Tuesday | Ships Wednesday |
| Order anytime Wednesday – Sunday | Ships following Monday |









